There is a new trend in anti-cancer therapeutics development: a targeted therapy and precision medicine that targets a subgroup of patients with specific biomarkers. An in vitro diagnostic (IVD) assay is required to identify a subgroup of cancer patients who would benefit from the targeted therapy, or not likely benefit, or have a high risk of side effects from the specific drug treatment. This IVD or medical device is called a companion diagnostic (CDx) assay. It is key to have a robust CDx assay or device for the success of targeted therapy and precision medicine.
This book covers the technical, historical, clinical, and regulatory aspects of CDx in precision medicine. Clearly, more and more newly developed oncology drugs will require accompanying CDx assays, and this book, with chapters contributed by renowned oncologists, provides a comprehensive foundation for the knowledge and application of CDx for precision medicine.
This book covers almost all fields of cancer genetics and genomics for personalized medicine. Surely, the one-fits-all approach does not work anymore for disease treatment. Targeted therapy or precision medicine or personalized medicine is becoming a standard for many disease treatments including cancer. However, how much do we know about the personalized medicine approach? This book will help undergraduate/graduate students, professional researchers, and clinicians to better understand the key concept of personalized medicine.
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